產(chǎn)品信息

TGF-β家族成員廣泛存在于從果蠅到人多種生物的 各種組織中，對正常細(xì)胞、癌變細(xì)胞都有著顯著作用。TGF-β除了影響細(xì)胞的增殖、分化，還在胚胎發(fā)育、胞外基質(zhì)形成、 骨的形成和重建等方面起著重要作用。

Dorsomorphin:
A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2, ALK-3 and ALK-6). Also inhibits AMP-activated protein kinase (AMPK). 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE

Ref: Yu et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat. Chem. Biol. 4 33, 2008.

Purity:
Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.

Biological Activity:
Not determined.

重慶市華雅干細(xì)胞技術(shù)有限公司